Deciphering subgenome differentiation and centromere dynamics in asymmetric meiosis of dogroses

This project investigates the genomic and cytogenetic basis of asymmetric meiosis in polyploid dogroses (Rosa sect. Caninae), a unique reproductive system where only two chromosome sets recombine while others are transmitted uniparentally.

By integrating high-quality genome assemblies, transcriptomics, and advanced cytogenetic approaches, the study aims to characterize subgenome differentiation, centromere composition, and their roles in chromosome pairing and segregation. Special focus is placed on the bimodal structure of centromeres, dominated either by satellite repeats (CANR4) or retroelements (ATHILA), and their potential influence on meiotic behavior. Through comparative analyses of dogroses, their synthetic hybrids, and related diploid species, the project seeks to uncover the genetic and epigenetic mechanisms underlying asymmetric meiosis, recombination, and genome evolution in polyploid plants.